Lifesciences Pvt. Ltd.


Brand Name Neutocid-LS
Generic Name Rebeprazole 20 mg +Levosulpiride 75 mg SR
Description Rabeprazole belongs to a class of anti secretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds.
Levosulpiride is more selective and acts primarily as a dopamine D2 antagonist.
Packaging 1*10
Pack Size 10
Dosage Rabeprazole 20mg
Theripti Use Exerts prokinetic action through dual mechanism:
-As a Dopamine 2 receptor antagonist
-As a Serotonin 5HT$ recetor agonist
At a dosage of 75 mg SR daily, Levosulpiride accelerates gastric and gallbladder emptying
More Effective in reducing Symptoms of dyspepsia, as compared to other dopamine antagonists
Safe and Effective for long-term maintenance therapy of reflux esophagitis.
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